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Chemoreceptor Responsiveness at Sea Level Does Not Predict the Pulmonary Pressure Response to High Altitude.
BACKGROUND:The hypoxic ventilatory response (HVR) at sea level (SL) is moderately predictive of the change in pulmonary artery systolic …
Ryan L Hoiland, Glen E Foster, Joseph Donnelly, Mike Stembridge, Chris K Willie, Kurt J Smith, Nia C Lewis, Samuel J E Lucas, Jim D Cotter, David J Yeoman, Kate N Thomas, Trevor A Day, Mike M Tymko, Keith R Burgess, Philip N Ainslie
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End tidal-to-arterial CO$_textrm2$ and O$_textrm2$ gas gradients at low- and high-altitude during dynamic end-tidal forcing.
We sought to characterize and quantify the performance of a portable dynamic end-tidal forcing (DEF) system in controlling the partial …
Michael M Tymko, Philip N Ainslie, David B MacLeod, Chris K Willie, Glen E Foster
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The contribution of arterial blood gases in cerebral blood flow regulation and fuel utilization in man at high altitude.
The effects of partial acclimatization to high altitude (HA; 5,050 m) on cerebral metabolism and cerebrovascular function have not been …
Christopher K Willie, David B MacLeod, Kurt J Smith, Nia C Lewis, Glen E Foster, Keita Ikeda, Ryan L Hoiland, Philip N Ainslie
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Oxygen cost of exercise hyperpnoea is greater in women compared with men
KEY POINTS: The oxygen cost of breathing represents a significant fraction of total oxygen uptake during intense exercise. At a given …
Paolo B. Dominelli, Jacqueline N. Render, Yannick Molgat-Seon, Glen E. Foster, Lee M. Romer, A. William Sheel
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Hypoxia, not pulmonary vascular pressure, induces blood flow through intrapulmonary arteriovenous anastomoses.
KEY POINTS:Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown …
Joshua C Tremblay, Andrew T Lovering, Philip N Ainslie, Mike Stembridge, Keith R Burgess, Akke Bakker, Joseph Donnelly, Samuel J E Lucas, Nia C S Lewis, Paolo B Dominelli, William R Henderson, Giulio S Dominelli, A William Sheel, Glen E Foster
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Impact of hypocapnia and cerebral perfusion on orthostatic tolerance.
We examined two novel hypotheses: (1) that orthostatic tolerance (OT) would be prolonged when hyperventilatory-induced hypocapnia (and …
Nia C S Lewis, Anthony R Bain, David B MacLeod, Kevin W Wildfong, Kurt J Smith, Christopher K Willie, Marit L Sanders, Tianne Numan, Shawnda A Morrison, Glen E Foster, Julian M Stewart, Philip N Ainslie
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Precise mimicking of exercise hyperpnea to investigate the oxygen cost of breathing
The oxygen cost of exercise hyperpnea (V˙(O2 RM)) has been quantified using a variety of techniques with inconsistent findings. …
P. B. Dominelli, J. N. Render, Y. Molgat-Seon, G. E. Foster, A. W. Sheel
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Pulmonary mechanics and gas exchange during exercise in Kenyan distance runners
PURPOSE: The purpose of this study was to determine arterial blood gases, the mechanical limits for generating expiratory flow and the …
Glen E. Foster, Michael S. Koehle, Paolo B. Dominelli, Francis M. Mwangi, Vincent O. Onywera, Michael K. Boit, Joshua C. Tremblay, Chepleting Boit, A. William Sheel
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Resting pulmonary haemodynamics and shunting: a comparison of sea-level inhabitants to high altitude Sherpas
The incidence of blood flow through intracardiac shunt and intrapulmonary arteriovenous anastomoses (IPAVA) may differ between Sherpas …
Glen E. Foster, Philip N. Ainslie, Mike Stembridge, Trevor A. Day, Akke Bakker, Samuel J. E. Lucas, Nia C. S. Lewis, David B. MacLeod, Andrew T. Lovering
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Exercise-induced arterial hypoxemia is unaffected by intense physical training: a case report
Paolo B Dominelli, Glen E Foster, Giulio S Dominelli, William R Henderson, Michael S Koehle, Donald C McKenzie, A William Sheel
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