Hypercapnia

Acute intermittent hypercapnic hypoxia and cerebral neurovascular coupling in males and females
The decline in cognition observed in obstructive sleep apnea is linked to intermittent hypercapnic hypoxia (IHH), which is known to …
Tyler D. Vermeulen, Jenna Benbaruj, Courtney V. Brown, Brooke M. Shafer, John S. Floras, Glen E. Foster
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Acute intermittent hypercapnic hypoxia and cerebral neurovascular coupling in males and females
Influence of methazolamide on the human control of breathing: A comparison to acetazolamide
New Findings What is the central question of this study? Acetazolamide and methazolamide both reduce hypoxic pulmonary vasoconstriction …
Luc J. Teppema, Lindsey M. Boulet, Heather K. Hackett, Paolo B. Dominelli, William S. Cheyne, Giulio S. Dominelli, Erik R. Swenson, Glen E. Foster
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Influence of methazolamide on the human control of breathing: A comparison to acetazolamide
Peripheral chemoreflex contribution to ventilatory long-term facilitation induced by acute intermittent hypercapnic hypoxia in males and females
Key points Ventilatory long-term facilitation (vLTF) refers to respiratory neuroplasticity that develops following intermittent hypoxia …
Tyler D. Vermeulen, Jenna Benbaruj, Courtney V. Brown, Brooke M. Shafer, John S. Floras, Glen E. Foster
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Peripheral chemoreflex contribution to ventilatory long-term facilitation induced by acute intermittent hypercapnic hypoxia in males and females
Ventilatory responses to acute hypoxia and hypercapnia in humans with a patent foramen ovale
Subjects with a patent foramen ovale (PFO) have blunted ventilatory acclimatization to high altitude, compared to subjects without PFO. …
James T. Davis, Lindsey M. Boulet, Alyssa M. Hardin, Alex J. Chang, Andrew T. Lovering, Glen Edward Foster
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Influence of myocardial oxygen demand on the coronary vascular response to arterial blood gas changes in humans.
It remains unclear if the human coronary vasculature is inherently sensitive to changes in arterial PO2and PCO2or if coronary vascular …
Tyler Dennis Vermeulen, Lindsey M Boulet, Mike Stembridge, Alexandra Mackenzie Williams, James D Anholm, Prajan Subedi, Chris Gasho, Ainslie Philip, Eric O Feigl, Glen Edward Foster
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The effect of consistent practice of yogic breathing exercises on the human cardiorespiratory system
Joshua A A McKay, Cara L McCulloch, Jordan S Querido, Glen E Foster, Michael S Koehle, A William Sheel
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The effects of graded changes in oxygen and carbon dioxide tension on coronary blood velocity independent of myocardial energy demand.
In humans, coronary blood flow is tightly regulated by microvessels within the myocardium to match myocardial energy demand. However, …
Lindsey M Boulet, Mike Stembridge, Michael M Tymko, Joshua C Tremblay, Glen E Foster
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What role for hypercapnia in obstructive sleep apnea?
TO THE EDITOR: The question raised by Wang et al.(5) in their recent Viewpoint is important inasmuch as apneic events in obstructive …
Julien V Brugniaux, Glen E Foster, Andrew E Beaudin
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Role of CO2 in the cerebral hyperemic response to incremental normoxic and hyperoxic exercise.
Cerebral blood flow (CBF) is temporally related to exercise-induced changes in partial pressure of end-tidal carbon dioxide (PetCO2 ); …
Kurt J Smith, K W Wildfong, R L Hoiland, M Harper, N C Lewis, A Pool, S L Smith, T Kuca, G E Foster, P N Ainslie
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Chemoreceptor Responsiveness at Sea Level Does Not Predict the Pulmonary Pressure Response to High Altitude.
BACKGROUND:The hypoxic ventilatory response (HVR) at sea level (SL) is moderately predictive of the change in pulmonary artery systolic …
Ryan L Hoiland, Glen E Foster, Joseph Donnelly, Mike Stembridge, Chris K Willie, Kurt J Smith, Nia C Lewis, Samuel J E Lucas, Jim D Cotter, David J Yeoman, Kate N Thomas, Trevor A Day, Mike M Tymko, Keith R Burgess, Philip N Ainslie
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