hypoxia

The effects of graded changes in oxygen and carbon dioxide tension on coronary blood velocity independent of myocardial energy demand.
In humans, coronary blood flow is tightly regulated by microvessels within the myocardium to match myocardial energy demand. However, …
Lindsey M Boulet, Mike Stembridge, Michael M Tymko, Joshua C Tremblay, Glen E Foster
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Comparing and characterizing transient and steady-state tests of the peripheral chemoreflex in humans
Jamie R Pfoh, Michael M Tymko, Maria Abrosimova, Lindsey M Boulet, Glen E Foster, Anthony R Bain, Philip N Ainslie, Craig D Steinback, Christina D Bruce, Trevor A Day
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Changes in left ventricular function and coronary blood flow velocity during isocapnic hypoxia: A cardiac magnetic resonance imaging study
Glen E Foster, Zixin Deng, Lindsey M Boulet, Puja K Mehta, J Wei, Zhaoyang Fan, Rohan Dharmakumar, C N B Merz, Debiao Li, Michael D Nelson
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Effect on Intermittent Hypoxia on Plasma Exosomal Micro RNA Signature and Endothelial Function in Healthy Adults
STUDY OBJECTIVE: Intermittent hypoxia (IH) is associated with increased risk of cardiovascular disease. Exosomes are secreted by most …
Abdelnaby Khalyfa, Chunling Zhang, Ahamed A. Khalyfa, Glen E. Foster, Andrew E. Beaudin, Jorge Andrade, Patrick J. Hanly, Marc J. Poulin, David Gozal
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Measuring the human ventilatory and cerebral blood flow response to CO$_textrm2$: a technical consideration for the end-tidal-to-arterial gas gradient
Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E Foster
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Changes in cerebral vascular reactivity and structure following prolonged exposure to high altitude in humans
Although high-altitude exposure can lead to neurocognitive impairment, even upon return to sea level, it remains unclear the extent to …
Glen E. Foster, Jodie Davies-Thompson, Paolo B. Dominelli, Manraj K. S. Heran, Joseph Donnelly, Gregory R. duManoir, Philip N. Ainslie, Alexander Rauscher, A. William Sheel
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Chemoreceptor Responsiveness at Sea Level Does Not Predict the Pulmonary Pressure Response to High Altitude.
BACKGROUND:The hypoxic ventilatory response (HVR) at sea level (SL) is moderately predictive of the change in pulmonary artery systolic …
Ryan L Hoiland, Glen E Foster, Joseph Donnelly, Mike Stembridge, Chris K Willie, Kurt J Smith, Nia C Lewis, Samuel J E Lucas, Jim D Cotter, David J Yeoman, Kate N Thomas, Trevor A Day, Mike M Tymko, Keith R Burgess, Philip N Ainslie
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End tidal-to-arterial CO$_textrm2$ and O$_textrm2$ gas gradients at low- and high-altitude during dynamic end-tidal forcing.
We sought to characterize and quantify the performance of a portable dynamic end-tidal forcing (DEF) system in controlling the partial …
Michael M Tymko, Philip N Ainslie, David B MacLeod, Chris K Willie, Glen E Foster
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Hypoxia, not pulmonary vascular pressure, induces blood flow through intrapulmonary arteriovenous anastomoses.
KEY POINTS:Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown …
Joshua C Tremblay, Andrew T Lovering, Philip N Ainslie, Mike Stembridge, Keith R Burgess, Akke Bakker, Joseph Donnelly, Samuel J E Lucas, Nia C S Lewis, Paolo B Dominelli, William R Henderson, Giulio S Dominelli, A William Sheel, Glen E Foster
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Resting pulmonary haemodynamics and shunting: a comparison of sea-level inhabitants to high altitude Sherpas
The incidence of blood flow through intracardiac shunt and intrapulmonary arteriovenous anastomoses (IPAVA) may differ between Sherpas …
Glen E. Foster, Philip N. Ainslie, Mike Stembridge, Trevor A. Day, Akke Bakker, Samuel J. E. Lucas, Nia C. S. Lewis, David B. MacLeod, Andrew T. Lovering
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