Sleep Apnea

Angiotensin II-Type I Receptor Antagonism Does Not Influence the Chemoreceptor Reflex or Hypoxia-Induced Central Sleep Apnea in Men
Components of the renin-angiotensin system situated within the carotid body or central nervous system may promote hypoxia-induced …
Courtney V. Brown, Lindsey M. Boulet, Tyler D. Vermeulen, Scott A. Sands, Richard J. A. Wilson, Najib T. Ayas, John S. Floras, Glen E. Foster
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Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia
Intermittent hypoxia (IH) is associated with increased endothelial dysfunction and cardiovascular disorders. Exosomes released in …
Abdelnaby Khalyfa, Nina Youssefnia, Glen E. Foster, Andrew E. Beaudin, Zhuanghong Qiao, Vincent Pialoux, Matiram Pun, Patrick J. Hanly, Leila Kheirandish-Gozal, Marc J. Poulin, David Gozal
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Intermittent hypoxia and arterial blood pressure control in humans: role of the peripheral vasculature and carotid baroreflex.
Intermittent hypoxia (IH) occurs in association with obstructive sleep apnea and likely contributes to the pathogenesis of …
Joshua C Tremblay, Lindsey M Boulet, Michael M Tymko, Glen E Foster
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What role for hypercapnia in obstructive sleep apnea?
TO THE EDITOR: The question raised by Wang et al.(5) in their recent Viewpoint is important inasmuch as apneic events in obstructive …
Julien V Brugniaux, Glen E Foster, Andrew E Beaudin
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Effect on Intermittent Hypoxia on Plasma Exosomal Micro RNA Signature and Endothelial Function in Healthy Adults
STUDY OBJECTIVE: Intermittent hypoxia (IH) is associated with increased risk of cardiovascular disease. Exosomes are secreted by most …
Abdelnaby Khalyfa, Chunling Zhang, Ahamed A. Khalyfa, Glen E. Foster, Andrew E. Beaudin, Jorge Andrade, Patrick J. Hanly, Marc J. Poulin, David Gozal
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Effects of exposure to intermittent hypoxia on oxidative stress and acute hypoxic ventilatory response in humans.
RATIONALE:Periodic occlusion of the upper airway in patients with obstructive sleep apnea leads to chronic intermittent hypoxia, which …
Vincent Pialoux, Patrick J Hanly, Glen E Foster, Julien V Brugniaux, Andrew E Beaudin, Sara E Hartmann, Matiram Pun, Cailean T Duggan, Marc J Poulin
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Cardiovascular and cerebrovascular responses to acute hypoxia following exposure to intermittent hypoxia in healthy humans
Intermittent hypoxia (IH) is thought to be responsible for many of the long-term cardiovascular consequences associated with …
Glen E. Foster, Julien V. Brugniaux, Vincent Pialoux, Cailean T. C. Duggan, Patrick J. Hanly, Sofia B. Ahmed, Marc J. Poulin
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Ventilatory and cerebrovascular responses to hypercapnia in patients with obstructive sleep apnoea: effect of CPAP therapy.
The purpose of this study was to assess whether the cerebrovascular response to hypercapnia is blunted in OSA patients and if this …
Glen E Foster, Patrick J Hanly, Michele Ostrowski, Marc J Poulin
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Ventilatory and blood pressure responses to isocapnic hypoxia in OSA patients.
Glen E Foster, Patrick J Hanly, Michele Ostrowski, Marc J Poulin
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Effects of continuous positive airway pressure on cerebral vascular response to hypoxia in patients with obstructive sleep apnea.
RATIONALE:The mechanism leading to increased risk of stroke in patients with obstructive sleep apnea (OSA) is unknown. It may occur …
Glen E Foster, Patrick J Hanly, Michele Ostrowski, Marc J Poulin
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